St. Jude Children’s Research Hospital is the largest and the only U.S. National Cancer Institute-designated comprehensive cancer center in the United States. The first successful cure for childhood ALL came from St. Jude and currently their cure rate for ALL is approximately 90%. St. Jude is a charity hospital, and one of its missions is to help improve the cure for childhood cancer worldwide through its Global Program. Together with the VIVA Foundation, St. Jude hopes to develop Singapore not only as a world-class centre for the treatment of childhood cancers and the training of paediatric oncologists in Asia and beyond, but also as a coordinating centre for research in childhood cancer in Asia. This Forum is the twelfth of such efforts to bring the Asian groups to hub together under one roof.